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Hwa-Sup Shin Selected Research

Heart Injuries

5/2017Cardioprotective effect of KR-33889, a novel PARP inhibitor, against oxidative stress-induced apoptosis in H9c2 cells and isolated rat hearts.
8/2010Cardioprotective effects of the novel Na+/H+ exchanger-1 inhibitor KR-32560 in a perfused rat heart model of global ischemia and reperfusion: Involvement of the Akt-GSK-3beta cell survival pathway and antioxidant enzyme.
2/2009KR-31761, a novel K+(ATP)-channel opener, exerts cardioprotective effects by opening both mitochondrial K+(ATP) and Sarcolemmal K+(ATP) channels in rat models of ischemia/reperfusion-induced heart injury.
4/2008KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury.
5/2007Cardioprotective effects of BMS-180448, a prototype mitoK(ATP) channel opener, and the role of salvage kinases, in the rat model of global ischemia and reperfusion heart injury.
12/2005Cardioprotective effects of [5-(2-methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an anesthetized rat model of ischemia and reperfusion heart injury.
8/2005Effects of [5-(2-methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32560), a novel sodium/hydrogen exchanger-1 inhibitor, on myocardial infarct size and ventricular arrhythmias in a rat model of ischemia/reperfusion heart injury.

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Hwa-Sup Shin Research Topics

Disease

9Ischemia
05/2014 - 08/2005
7Heart Injuries
05/2017 - 08/2005
5Infarction (Infarctions)
03/2014 - 08/2005
3Myocardial Infarction
03/2014 - 07/2003
2Atherosclerosis
10/2017 - 05/2007
2Neoplasms (Cancer)
10/2017 - 10/2014
2Hyperplasia
10/2017 - 09/2009
2Reperfusion Injury
03/2014 - 01/2005
2Contracture
02/2009 - 04/2008
2Ventricular Fibrillation
12/2005 - 08/2005
2Ventricular Tachycardia
12/2005 - 08/2005
2Premature Cardiac Complexes (Extrasystoles)
12/2005 - 08/2005
1Vascular Remodeling
10/2017
1Obesity
10/2017
1Neointima
10/2017
1Myocardial Ischemia (Ischemic Heart Diseases)
05/2017
1Atopic Dermatitis (Atopic Eczema)
01/2016
1Dementia (Dementias)
10/2014
1Heart Diseases (Heart Disease)
03/2014
1Arthritis (Polyarthritis)
09/2009
1Experimental Arthritis
09/2009
1Hypertension (High Blood Pressure)
07/2003

Drug/Important Bio-Agent (IBA)

4Adenosine Triphosphate (ATP)IBA
02/2009 - 01/2005
3furanIBA
08/2010 - 08/2005
3Guanidine (Guanidine Nitrate)FDA Link
08/2010 - 08/2005
2Platelet-Derived Growth FactorIBA
10/2017 - 05/2007
2Becaplermin (PDGF-BB)FDA Link
10/2017 - 05/2007
2AntioxidantsIBA
10/2014 - 08/2010
2EnzymesIBA
04/2013 - 08/2010
2KR-32560IBA
08/2010 - 08/2005
2Proteins (Proteins, Gene)FDA Link
08/2010 - 05/2007
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
02/2009 - 04/2008
2BMS 180448IBA
05/2007 - 07/2003
2HydrogenIBA
12/2005 - 08/2005
2SodiumIBA
12/2005 - 08/2005
13-methylquercetinIBA
10/2017
1p-coumaric acidIBA
10/2017
1Mitogen-Activated Protein KinasesIBA
10/2017
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
10/2017
1p38 Mitogen-Activated Protein KinasesIBA
10/2017
1ethyl acetateIBA
10/2017
12- (methoxycarbonyl(4- methoxyphenyl)methylsulfanyl)- 1H- benzimidazole- 4- carboxylic acid amideIBA
05/2017
1Dinitrochlorobenzene (DNCB)IBA
01/2016
1hispidinIBA
10/2014
1rhamnetinIBA
05/2014
1Krebs-Henseleit solutionIBA
03/2014
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
03/2014
1cordycepinIBA
03/2014
1DNA (Deoxyribonucleic Acid)IBA
04/2013
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
04/2013
1Adenosine (Adenocard)FDA LinkGeneric
04/2013
1Diphosphates (Pyrophosphates)IBA
04/2013
1Ribose (D-Ribose)IBA
04/2013
1Matrix Metalloproteinases (MMPs)IBA
09/2009
1Collagen Type II (Type II Collagen)IBA
09/2009
1CurcuminIBA
09/2009
1HMR 1098IBA
02/2009
1KR-31761IBA
02/2009
1KR-31762IBA
04/2008
1KATP ChannelsIBA
04/2008
1Phosphotransferases (Kinase)IBA
05/2007
1mitochondrial K(ATP) channelIBA
05/2007
1KR-32568IBA
12/2005
1BMS 191095IBA
01/2005
1Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2003
1Vasoconstrictor AgentsIBA
07/2003
1Vasodilator Agents (Vasodilators)IBA
07/2003
1Adenylyl Cyclases (Adenylyl Cyclase)IBA
07/2003

Therapy/Procedure

2Oral Administration
10/2017 - 09/2009
1Traditional Medicine (Folk Remedies)
10/2017